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משתמש:מגזין יהלום/תרגומים

מתוך ויקיפדיה, האנציקלופדיה החופשית

תבנית:Infobox scientistSarah Amalia Teichmann (born 1975)[1] תבנית:Post-nominals[2] is head of cellular genetics at the Wellcome Sanger Institute[3] and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI).[4][5] She is serves as director of research (equivalent to Professor)[6] in the Cavendish Laboratory,[7] at the University of Cambridge and a senior research fellow at Churchill College, Cambridge.[8][9]

Education[עריכת קוד מקור | עריכה]

Teichmann was educated at the European School, Karlsruhe in Germany from 1981 to 1993 where she completed the European Baccalaureate in 1993.[10] Teichmann went on to study the Natural Sciences Tripos at Trinity College, Cambridge and was awarded a first class Bachelor of Arts degree in 1996. In 1999, she completed her PhD supervised by Cyrus Chothia[11] at the Laboratory of Molecular Biology (LMB) on genome evolution.[12]

Career and research[עריכת קוד מקור | עריכה]

Following her PhD, Teichmann did postdoctoral research supervised by Janet Thornton at University College London[4] and funded by the Beit Memorial Fellowships for Medical Research. From 2001-2012, she was a Medical Research Council (MRC) Programme Leader, studying patterns in protein interactions and transcriptional regulatory networks.[13][14]

In 2013 Teichmann was appointed a joint position at the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EMBL-EBI). From 2005 to 2015 she served as a teaching fellow and director of studies at Trinity College, Cambridge. Since 2016 Teichmann has served as the head of Cellular Genetics at the Wellcome Trust Sanger Institute[3] and a visiting research group leader at the EBI.[5]

Teichmann's research[15][16][17][18] investigates gene expression[19][20][21] and protein complex assembly[22] using both wet laboratory and computational biology techniques.[23] In particular her research group: תבנית:Centered pull quote

Teichmann's research has been funded by the European Research Council (ERC), the Medical Research Council (MRC), the Biotechnology and Biological Sciences Research Council (BBSRC),[24] the Wellcome Trust, the European Molecular Biology Organization (EMBO), the Framework Programmes for Research and Technological Development and the European Cooperation in Science and Technology (COST).[10]

תבנית:As of Teichmann has supervised several PhD students to completion[25][10][26][27][28][29][30][31][32][33] and several postdoctoral researchers who have gone on to become Principal investigators (PIs).[10][34][35][36]

Awards and honours[עריכת קוד מקור | עריכה]

Teichmann has won a number of awards. In 2010, she was awarded Colworth Medal from the Biochemical Society.[37][38] In 2012, Teichman was awarded the Francis Crick Medal and Lecture, membership of the European Molecular Biology Organization (EMBO)[39] and the Lister Prize from the Lister Institute of Preventive Medicine.[40] In 2015 she was awarded the Michael and Kate Bárány Award for young investigators by the Biophysical Society[41] and the EMBO Gold Medal. Teichmann was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2015. Her citation on election reads: תבנית:Centred pull quote Teichmann has also been an activist for women's careers in science through enabling scientists in families to advance their careers while working part-time.[42] She chaired a Sex in Science debate at the Wellcome Trust on balancing family life with working in research.תבנית:Fact Teichmann was elected an ISCB Fellow in 2016 by the International Society for Computational Biology.[43]

In 2020, Teichmann was recognised on The Times 'Science Power List' for her work on the Human Cell Atlas.[44]

Personal life[עריכת קוד מקור | עריכה]

Teichmann has two daughters.[45][46] Teichmann is the co-author of the children's language education novel Teenage Detectives,[47] which she wrote as a teenager together with her mother Dr. Virginia Teichmann, an English-language university lecturer in Karlsruhe.[48]

References[עריכת קוד מקור | עריכה]

תבנית:Scholia

  1. ^ Teichmann, Sarah (2007). "Sarah Amalia Teichmann PhD MA BA (Hons cantab) CV" (PDF). mrc-lmb.cam.ac.uk. Laboratory of Molecular Biology. אורכב מ-המקור (PDF) ב-2013-02-26.
  2. ^ Anon (2015). "Dr Sarah Teichmann FMedSci". acmedsci.ac.uk. London: Academy of Medical Sciences. אורכב מ-המקור ב-2015-07-06.
  3. ^ 1 2 "Dr Sarah Teichmann, FMedSci, Head of Cellular Genetics". Cambridge: sanger.ac.uk. אורכב מ-המקור ב-2016-04-15.
  4. ^ 1 2 Marx, Vivien (2016). "The Author File: Sarah Teichmann". Nature Methods. 13 (4): 279. doi:10.1038/nmeth.3808. ISSN 1548-7091. PMID 27203785.
  5. ^ 1 2 שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם ebiabout
  6. ^ Anon (2013). "Job titles and duties at the University of Cambridge". University of Cambridge. אורכב מ-המקור ב-2013-07-03.
  7. ^ Anon (2015). "Dr Sarah Teichmann FMedSci". tcm.phy.cam.ac.uk. Cambridge. אורכב מ-המקור ב-2015-09-12.
  8. ^ "People – Churchill College". www.chu.cam.ac.uk.
  9. ^ Dhillon, Paraminder; Teichmann, Sarah A. (2019). "In conversation with Sarah Teichmann". The FEBS Journal. 286 (8): 1445–1450. doi:10.1111/febs.14806. ISSN 1742-464X. PMID 31012289.
  10. ^ 1 2 3 4 Anon (2015). "Sarah Teichmann: 40th FEBS Congress - The Biochemical Basis of Life - Berlin, Germany". Federation of European Biochemical Societies. אורכב מ-המקור ב-2015-02-20.
  11. ^ Chothia, C; Gough, J; Vogel, C; Teichmann, S. A. (2003). "Evolution of the protein repertoire". Science. 300 (5626): 1701–3. doi:10.1126/science.1085371. PMID 12805536.
  12. ^ Teichmann, Sarah Amalia (1999). Genome evolution : analysing proteomes with new methods (PhD thesis). University of Cambridge. OCLC 894602472. תבנית:EThOS.
  13. ^ Babu, M. M.; Luscombe, N. M.; Aravind, L; Gerstein, M; Teichmann, S. A. (2004). "Structure and evolution of transcriptional regulatory networks". Current Opinion in Structural Biology. 14 (3): 283–91. CiteSeerX 10.1.1.471.9692. doi:10.1016/j.sbi.2004.05.004. PMID 15193307.
  14. ^ Luscombe, N. M.; Babu, M. M.; Yu, H; Snyder, M; Teichmann, S. A.; Gerstein, M (2004). "Genomic analysis of regulatory network dynamics reveals large topological changes". Nature. 431 (7006): 308–12. doi:10.1038/nature02782. PMID 15372033.
  15. ^ תבנית:ACM Portal
  16. ^ תבנית:DBLP
  17. ^ תבנית:Scopus id
  18. ^ תבנית:EuropePMC
  19. ^ Carninci, P; Kasukawa, T; Katayama, S; Gough, J; Frith, M. C.; Maeda, N; Oyama, R; Ravasi, T; Lenhard, B; Wells, C; Kodzius, R; Shimokawa, K; Bajic, V. B.; Brenner, S. E.; Batalov, S; Forrest, A. R.; Zavolan, M; Davis, M. J.; Wilming, L. G.; Aidinis, V; Allen, J. E.; Ambesi-Impiombato, A; Apweiler, R; Aturaliya, R. N.; Bailey, T. L.; Bansal, M; Baxter, L; Beisel, K. W.; Bersano, T; et al. (2005). "The transcriptional landscape of the mammalian genome". Science. 309 (5740): 1559–63. doi:10.1126/science.1112014. PMID 16141072.
  20. ^ Drosophila 12 Genomes, Consortium; Clark, A. G.; Eisen, M. B.; Smith, D. R.; Bergman, C. M.; Oliver, B; Markow, T. A.; Kaufman, T. C.; Kellis, M; Gelbart, W; Iyer, V. N.; Pollard, D. A.; Sackton, T. B.; Larracuente, A. M.; Singh, N. D.; Abad, J. P.; Abt, D. N.; Adryan, B; Aguade, M; Akashi, H; Anderson, W. W.; Aquadro, C. F.; Ardell, D. H.; Arguello, R; Artieri, C. G.; Barbash, D. A.; Barker, D; Barsanti, P; Batterham, P; et al. (2007). "Evolution of genes and genomes on the Drosophila phylogeny". Nature. 450 (7167): 203–18. doi:10.1038/nature06341. PMID 17994087.
  21. ^ Wilson, D; Charoensawan, V; Kummerfeld, S. K.; Teichmann, S. A. (2008). "DBD--taxonomically broad transcription factor predictions: New content and functionality". Nucleic Acids Research. 36 (Database issue): D88–92. doi:10.1093/nar/gkm964. PMC 2238844. PMID 18073188.
  22. ^ Levy, E. D.; Teichmann, S (2013). "Structural, Evolutionary, and Assembly Principles of Protein Oligomerization". Oligomerization in Health and Disease. Progress in Molecular Biology and Translational Science. Vol. 117. pp. 25–51. doi:10.1016/B978-0-12-386931-9.00002-7. ISBN 9780123869319. PMID 23663964.
  23. ^ Perica, T; Kondo, Y; Tiwari, S. P.; McLaughlin, S. H.; Kemplen, K. R.; Zhang, X; Steward, A; Reuter, N; Clarke, J; Teichmann, S. A. (2014). "Evolution of oligomeric state through allosteric pathways that mimic ligand binding". Science. 346 (6216): 1254346. doi:10.1126/science.1254346. PMC 4337988. PMID 25525255.
  24. ^ Anon (2015). "UK Government research grants awarded to Sarah Teichmann". Research Councils UK. אורכב מ-המקור ב-2015-03-03.
  25. ^ Teichmann, Sarah (2015). "Alumni from Sarah Teichmann's Group". European Bioinformatics Institute. אורכב מ-המקור ב-2015-02-20.
  26. ^ שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם babuphd
  27. ^ Charoensawan, Varodom (2011). Evolution and dynamics of transcription factors and gene expression patterns. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890150091.
  28. ^ De, Subhajyoti (2008). Human genome evolution : investigating protein divergence, polymorphisms and genomic neighbourhood. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890154864.
  29. ^ Han, Jay (2007). Structure, function and evolution of protein-protein interactions (PhD thesis). University of Cambridge.
  30. ^ Kummerfeld, Sarah Kay (2006). Towards understanding the protein universe : genome-scale studies of evolution and gene regulation. ethos.bl.uk (PhD thesis). University of Cambridge.
  31. ^ Levy, Emmanuel Doram (2008). Classification, evolution, and assembly of protein complexes. ethos.bl.uk (PhD thesis). University of Cambridge.
  32. ^ Perica, Tina (2013). Evolutionary and structural dynamics of protein complexes (PhD thesis). University of Cambridge. OCLC 890148231.
  33. ^ Su, Jing (2012). Computational prediction of regulatory elements (PhD thesis). University of Cambridge.
  34. ^ Adryan, B; Teichmann, S. A. (2010). "The developmental expression dynamics of Drosophila melanogaster transcription factors". Genome Biology. 11 (4): R40. doi:10.1186/gb-2010-11-4-r40. PMC 2884543. PMID 20384991.
  35. ^ Gsponer, J; Futschik, M. E.; Teichmann, S. A.; Babu, M. M. (2008). "Tight regulation of unstructured proteins: From transcript synthesis to protein degradation". Science. 322 (5906): 1365–8. doi:10.1126/science.1163581. PMC 2803065. PMID 19039133.
  36. ^ Hebenstreit, D; Gu, M; Haider, S; Turner, D. J.; Liò, P; Teichmann, S. A. (2011). "EpiChIP: Gene-by-gene quantification of epigenetic modification levels". Nucleic Acids Research. 39 (5): e27. doi:10.1093/nar/gkq1226. PMC 3061070. PMID 21131282.
  37. ^ שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם heirloom
  38. ^ Anon (2015). "Women at Cambridge: Sarah Amalia Teichmann". University of Cambridge. אורכב מ-המקור ב-2015-02-20.
  39. ^ שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם embom
  40. ^ שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם lister
  41. ^ "Biophysical Society Names 2015 Award Recipients" (PDF). Biophysical Society.
  42. ^ Gaskell & Kostic (2015). "The Unstoppable Sarah Teichmann on Programing, Motherhood, and Protein Complex Assembly:The Female Scientist". Cell. אורכב מ-המקור ב-2016-04-15. נבדק ב-2015-11-25.
  43. ^ Anon (2017). "ISCB Fellows". iscb.org. International Society for Computational Biology. אורכב מ-המקור ב-2017-03-20.
  44. ^ Franklin-Wallis, Oliver (23 במאי 2020). "From pandemics to cancer: the science power list". The Times (באנגלית). ISSN 0140-0460. נבדק ב-2020-05-26. {{cite news}}: (עזרה)תחזוקה - ציטוט: url-status (link)
  45. ^ שגיאת ציטוט: תג <ref> לא תקין; לא נכתב טקסט עבור הערות השוליים בשם 4am
  46. ^ Pain, Elisabeth (2015). "Harnessing computer power to understand biology". Science. doi:10.1126/science.caredit.a1500172.
  47. ^ Teichmann, Sarah; Teichmann, Virginia (1991). Cornelsen English Library - Fiction: 8. Schuljahr, Stufe 1 - Teenage Detectives: Textheft. Mit Aufgaben und Activities. Germany: Cornelsen Verlag. ISBN 978-3464053362.
  48. ^ Anon. "The Honeycomb: Dr. Virginia Teichmann: Word Lover" (PDF). expat-karlsruhe.com. נבדק ב-2015-12-07.

תבנית:ISCB Fellows תבנית:FRS 2020 תבנית:Authority control


[[Category:Jewish scientists]] [[Category:Living people]] [[Category:German bioinformaticians]] [[Category:Wellcome Trust]] [[Category:Academics of the University of Cambridge]] [[Category:Fellows of Trinity College, Cambridge]] [[Category:Alumni of University College London]] [[Category:Members of the European Molecular Biology Organization]] [[Category:Fellows of the Academy of Medical Sciences]] [[Category:1975 births]] [[Category:Fellows of the International Society for Computational Biology]] [[Category:Alumni of the European Schools]] }}

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