משתמש:Catadura/אלברט גרינשפון
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דף זה אינו ערך אנציקלופדי
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| דף זה אינו ערך אנציקלופדי | |
אלברט גרינשפון[עריכת קוד מקור | עריכה]
ד"ר אלברט גרינשפון הוא רופא בכיר וחוקר בתחום סרטן השד, סרטן המעי הגס, במכון שרת לאונקולוגיה בבית חולים הדסה עין כרם בירושלים. אלברט נולד בשנת 1985, שירת כרופא צבאי בדרגת רב סרן בצה"ל בשריון ובפיקוד העורף. השתתף במשלחת חילוץ של פיקוד העורף אחרי רעידת אדמה נפאל. במהלך הקריירה שלו, הוא עשה השתלמויות מקצועיות באנגליה ובארצות הברית. ד"ר גרינשפון פרסם שורה ארוכה של מחקרים בתחום הסרטן. חלק ממחקריו עוסקים בחקר DNA חופשי בדם של סרטן (מחלה).
Publications[עריכת קוד מקור | עריכה]
1. Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants Lambertini M, Ceppi M, Hamy AS, Caron O, Poorvu PD, Carrasco E, Grinshpun A, Punie K, Rousset-Jablonski C, Ferrari A, Paluch-Shimon S, Toss A, Senechal C, Puglisi F, Pogoda K, PérezFidalgo JA, De Marchis L, Ponzone R, Livraghi L, Estevez-Diz MDP, Villarreal-Garza C, Dieci MV, Clatot F, Duhoux FP, Graffeo R, Teixeira L, Córdoba O, Sonnenblick A, Ferreira AR, Partridge AH, Di Meglio A, Saule C, Peccatori FA, Bruzzone M, t'Kint de Roodenbeke MD, Ameye L, Balmaña J, Del Mastro L, Azim HA Jr. NPJ Breast Cancer. 2021 Feb;7(1):16.
2. [ 18F]FDG -PET/CT uptake reveals a single metastasis inside vertebral hemangioma - Catch me if you scan Cohen Y, Grinshpun A, Meir K, Godefroy J. Eur J Nucl Med Mol Imaging. 2021 Feb 10. doi: 10.1007/s00259-021-05200-x. Epub ahead of print.
3. ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin Sadeh R, Sharkia I, Fialkoff G, Rahat A, Gutin J, Chappleboim A, Nitzan M, Fox-Fisher I, Neiman D, Meler G, Kamari Z, Yaish D, Peretz T, Hubert A, Cohen JE, Salah A, Temper M, Grinshpun A, Maoz M, Abu-Gazala S, Ben Ya'acov A, Shteyer E, Safadi R, Kaplan T, Shemer R, Planer D, Galun E, Glaser B, Zick A, Dor Y, Friedman N. Nat Biotechnol. 2021 Jan doi: 10.1038/s41587-020-00775-6. Epub ahead of print.
3-2021 4. Clinical Characteristics and Prognosis of Gastric Cancer Patients with BRCA 1/2 Germline Mutations: Report of Ten Cases and a Literature Review Halpern N, Grinshpun A, Boursi B, Golan T, Margalit O, Aderka D, Friedman E, Laitman Y, Hubert A, Kadouri L, Hamburger T, Barnes-Kedar I, Levi Z, Ben-Aharon I, Brenner B, Goldberg Y, Peretz T, Shacham-Shmueli E.
Onco Targets Ther. 2020 Nov;13:11637-11644. 5. Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations Lambertini M, Ameye L, Hamy AS, Zingarello A, Poorvu PD, Carrasco E, Grinshpun A, Han S, Rousset-Jablonski C, Ferrari A, Paluch-Shimon S, Cortesi L, Senechal C, Miolo G, Pogoda K, Pérez-Fidalgo JA, De Marchis L, Ponzone R, Livraghi L, Del Pilar Estevez-Diz M, Villarreal-Garza C, Dieci MV, Clatot F, Berlière M, Graffeo R, Teixeira L, Córdoba O, Sonnenblick A, Pais HL, Ignatiadis M, Paesmans M, Partridge AH,Caron O, Saule C, Del Mastro L, Peccatori FA, Azim HA. Journal of Clinical Oncology, 2020 Sept; 38:26, 3012-3023
6. A Protracted Course of COVID19 Infection in a Metastatic Breast Cancer Patient During CDK4/6 Inhibitor Therapy Grinshpun A, Merlet I, Fruchtman H, Nachman D. Frontiers in Oncology, 2020 Jun; 10:1085.
7. Mucinous Histology, BRCA1/2 Mutations, and Elevated Tumor Mutational Burden in Colorectal Cancer Harpaz N, Gatt YE, Granit RZ, Fruchtman H, Hubert A, and Grinshpun A. Journal of Oncology, 2020 Apr 25;6421205 8. Diagnostic Yield of Multigene Panel Testing in an Israeli Cohort: Enrichment of LowPenetrance Variants Bernstein-Molho R, Friedman E, Kedar I, Laitman Y, Allweis TM, Gal-Yam EN, Feldman HB, Grinshpun A, Halpern N, Hartmajer S, Kadouri L, Katz LH, Kaufman B, Laish I, Levanon K, Philipsborn SL, Ludman M, Moran G, Peretz T, Reinstein E, Levi GR, Safra T, Shkedi S, Vinkler C, Levy Z, Goldberg Y. Breast Cancer Res Treat, 2020 Jun;181(2):445-453
9. Circulating Breast-derived DNA Allows Universal Detection and Monitoring of Localized Breast Cancer Moss J*, Zick A*, Grinshpun A*, Carmon E, Maoz M, Ohana BL, Abraham O, Arieli O, Germansky L, Meir K, Glaser B, Shemer R, Uziely B, Dor Y. Annals of Oncology, 2020 Mar;31(3):395-403
- Equal contribution
10. Regulation of Heparanase in Diabetes-Associated Pancreatic Carcinoma Goldberg R, Meirovitz A, Abecassis A, Esther Hermano E, Rubinstein AM, Nahmias D, Grinshpun A, Peretz T, Elkin M. Frontiers in Oncology. 2019;9:1405
3-2021 11. Life and Death of Circulating Cell-Free DNA Kustanovich A, Shwarz R, Peretz T, Grinshpun A. Cancer Biology & Therapy. 2019;20(8):1057-1067. Review. 12. Intractable Hypokalemia: a Red Herring for Rapidly Evolving Ectopic Cushing's Syndrome Braun J, Grinshpun A, Atlan K, Sachar S, Knigen A, Yosha-Orpaz L, Grozinsky-Glasberg S, Khoury T, Nachman D. IMAJ, 2019 Jan;21:60-62
13. Beyond KRAS: Practical Molecular Targets in Pancreatic Adenocarcinoma Grinshpun A, Zarbiv Y, Roszik J, Subbiah V, Hubert A. Case Reports Oncology, 2019;12:7–13
14. Unemployment following breast cancer diagnosis: A population-based study Grinshpun A, Rottenberg Y. The Breast, 2018 Dec; 27;44:24-28
15. Comprehensive human cell-type methylation atlas allows identification of origins of circulating cell-free DNA in health and disease Moss J, Magenheim J, Neiman D, Korach A, Samet Y, Maoz M, Druid H, Arner P , Fu KY, Kiss E, Spalding K, Landesberg G, Zick A, Grinshpun A, Shapiro J, Grompe M, Wittenberg A, Glaser B, Shemer R, Kaplan T, Dor Y. Nature Communications, 2018 Nov; 29;9(1):5068
16. Ex vivo organ culture as potential prioritization tool for breast cancer targeted therapy Grinshpun A, Gavert N, Granit RZ, Masuri H, Ben-Porath I, Breuer S, Zick A, Rosenberg S, Maoz M, Granit A, Pikarsky P, Straussman R, Peretz T, Sonnenblick A. Cancer Biology & Therapy. 2018 Aug 3;19(8):645-648
17. Phenotypic characteristics of colorectal cancer in BRCA1/2 mutation carriers Grinshpun A, Halpern N, Granit RZ, Hubert A, Hamburger T, Laitman Y, Shacham-Shmueli E, Peerless Y, Friedman E, Peretz T. European J of Human Genetics, 2018 Mar; 26(3):382-386
18. Unemployment risk 2 years and 4 years following gastric cancer diagnosis: a populationbased study. Rottenberg Y, Jacobs JM, Ratzon NZ, Grinshpun A, Cohen M, Uzieli B, de Boer AG. J Cancer Survivor. 2017 Feb; 11(1):119-125
19. Tumor, metastasis and what's in between Grinshpun A, Ben-Porath I, Peretz T, Salmon A. Harefuah. 2013 Jan; 152(1):30-3, 59, 58. Review. 3-2021
20. Neonatal gene therapy of glycogen storage disease type Ia using a feline immunodeficiency virus-based vector Grinshpun A, Condiotti R, Waddington SN, Peer M, Zeig E, Peretz S, Simerzin A, Chou J, Pann CJ, Giladi H, Galun E. Molecular Therapy. 2010 Sep; 18(9):1592-8.
21. The elderly and access to the intensive care unit: the battle for the last bed Grinshpun A, Rubinow A.
הערות[עריכת קוד מקור | עריכה]
^https://www.hadassah.org.il/endinvasivebiopsynews/
^https://scholar.google.co.il/citations?user=teiDNfIAAAAJ&hl=en ^https://istudy.co.il/emed/course/index.php?categoryid=55 ^https://medpage.co.il/%d7%91%d7%93%d7%99%d7%a7%d7%aa-%d7%93%d7%9d-%d7%a8%d7%92%d7%99%d7%9c%d7%94-%d7%aa%d7%95%d7%9b%d7%9c-%d7%9c%d7%97%d7%a1%d7%95%d7%9a-%d7%91%d7%99%d7%95%d7%a4%d7%a1%d7%99%d7%94-%d7%9e%d7%9b%d7%90%d7%99/ ^https://www.haaretz.co.il/misc/1.1078053